Extended hepatectomy using preoperatively PTCD and PVE to treat patients with locally advanced hilar cholangiocarcinoma

Objective To assess the safety and efficacy of extended liver resection using preoperative PTCD (percutaneous transhepatic cholangial drainage) and PVE (portal vein embolization) to treat patients with locally advanced hilar cholangiocarcinoma. Methods We collected and analyzed the clinical data of 27 patients with Bismuth types Ⅲ and Ⅳ hilar cholangiocarcinoma who underwent extended hepatecomy using preoperative PTCD and PVE in our hospital. Results There were 21 patients with R0 resection and 6 patients with R1 resection. The mortality rate was 0%. Eight patients died of cancer recurrence. Conclusion Preoperative PTCD and PVE combined with extended hepatectomy were safe and efficacious in treating patients with locally advanced hilar cholangiocarcinoma, which resulted in potential cure. Key words: Percutaneous transhepatic biliary drainage, PTCD; Portal vein embolization, PVE; Extended hepatectomy; Hilar cholangiocarcinoma, advanced