Nomogram for Hepatic Venous Pressure Gradient in Cirrhotic Patients

Aim The hepatic venous pressure gradient (HVPG) plays an important role in the treatment and prognosis of patients with cirrhosis. The aim of our study is to develop and validate a nomogram for HVPG >12 mm Hg. Methods A retrospective study was performed to explore a nomogram for HVPG > 12 mm Hg in a training cohort and validated in another cohort. The discriminative ability and calibration of the nomogram were tested using the C-statistic, area under the curve (AUC) and calibration plots. Results The nomogram was based on portosystemic shunts identified on CT images, cirrhosis etiology and Child-Pugh grade. These parameters were significantly associated with HVPG >12 mm Hg (P Conclusions This nomogram is a convenient tool to predict HVPG >12 mm Hg in cirrhotic patients, and can help clinicians quickly identify decompensated cirrhotic patients. This article is protected by copyright. All rights reserved.