Location Of Carotid Stenosis And Ocular Blood Pressure

This paper shows how the ocular blood pressure (OBP) dynamics is affected by the level of carotid stenosis and its location in the carotid vascular system (CVS). The study is based on a mathematical model of the stenosis, usually located at the carotid bifurcation into the external and internal carotid arteries. The model is based on experimental data from in vitro studies. The stenosis is modelled as a nonlinear resistive element, causing a pressure drop in the blood flow over a local constriction. Such a pressure change affects the spectral contents of peripheral pressure waveforms, particularly the OBP waveform. These results are being used in our research on a method for early detection of stroke.