Abstract 16098: Risk Factors for Frequent Premature Atrial Complexes in a Ten Year Holter Cohort

Introduction: Frequent premature atrial complexes (fPACs) predict increased risk of Atrial Fibrillation (AF). Risk factors for fPACs are not well established. Hypothesis: Patients with fPACs (≥100/day) will differ significantly from those without fPACs (<100/day). Methods: Holter recordings obtained between 2000 and 2010 of 1357 veterans free of AF were analyzed for premature atrial activity. Holter groups with fPACs and infrequent PACs were compared for differences in baseline characteristics obtained from EMR. Statistical comparisons were made using Chi square and student t-tests. Multivariate logistic regression analysis was used adjust for confounders. Results: Mean age of the study population was 64.3 years and 93% were male. Ninety one percent had at least 1 PAC per 24 hour ECG study period. Patients with fPACs were older (mean age 71.4 versus 60.3 years) and had higher mean maximum and a lower mean minimum heart rate. Hypertension, CAD, CHF and COPD were significantly more prevalent in fPAC group. ...