Hearing profile of gold miners with and without tuberculosis

Objectives To compare the hearing of gold miners with and without tuberculosis (TB) to determine the effect of TB and its associated risk profile on hearing. Methods Audiological and medical surveillance data of 2698 South African gold miners for 2001–2009 were analysed in a retrospective cohort design. Hearing thresholds for the air conduction frequencies (0.5, 1, 2, 3, 4, 6, 8 kHz) in both ears were analysed together with biographical and occupational data. Subjects were divided into two experimental (single TB treatment, n=911 and multiple TB treatment, n=376) and one control group (n=1411). Comparisons between groups included (1) change from baseline to most recent audiogram, (2) most recent hearing thresholds and (3) most recent thresholds in a subset of noise exposed and unexposed groups. Results Hearing thresholds for the TB groups were significantly (p Conclusion Gold miners with TB, especially with more than one episode of TB, demonstrate significantly poorer hearing thresholds and more pronounced decline in hearing over time independent of noise exposure. The exact cause is likely a complex interaction between TB, including treatment, and its associated risk profile.