Cross-sectional imaging for assessing intestinal fibrosis in Crohn's disease.
2020
: More than 30% of Crohn's disease (CD) patients develop fibrotic strictures in the bowel as the disease progresses. Excessive deposition of extracellular matrix components in the submucosa, and smooth muscle hypertrophy/ hyperplasia are the main features of fibrosis in CD. Cross-sectional imaging technology provides a wealth of information on the anatomy, histological composition, and physiological function, allowing for a non-invasive and complete evaluation of associated abnormalities. This review summarizes the recent advances in and the potential technologies of cross-sectional imaging for assessing intestinal fibrosis in CD, including ultrasound imaging, computed tomography, and magnetic resonance imaging. This article is protected by copyright. All rights reserved.
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