POS-752 A review of 100 kidney transplants performed over 16 months ; a single center experience from an African country Abstract paid for submission 2020-A-WCN21-0206(100983862431)

Introduction: Access to kidney transplantation has always been a problem in the African countries A brief overview of 100 kidney transplants done at our facility in 16 months is presented forthwith Methods: All the Kidney transplants done between the period Nov 2018- October 2020 (100 cases) were included in thee analysis All the transplants were performed at a single center and the data were collected progressively during their Pre transplant evaluation, perioperative course and post op follow up All the patients with +Ve DSA titres underwent Plasmapheresis and received IVIg before the transplantation All the recipients and the donors undergoing transplants during were screened for COVID -19, 5 days prior to admission by RT PCR and CT chest plain All the patients received prophylaxis with favipiravir starting from the postop period and continued for 2 months at a dose of 200mg twice daily Results: All the cases were live donor kidney transplants with majority of the donors being 1stor 2nd degree relatives or spousal donors HBsAg +ve 2, HIV+Ve 3, 4 patients required pretransplant Parathyroidectomy for refractory hyperparathyroidism 3 patients required simulteneous native kidney nephrectomy, 8 patients had multiple renal vessels which were double barrelled and anastamosed lower urinary tract abnormalities 2 requiring simultaneous/subsequent repair 2 patients underwent 2nd transplant Most of the donors underwent laparoscopic nephrectomy 90% had good immediate graft function except in 10 patients, had DGF;9 of them improving over 2 -6 weeks 8 Graft biopsies done ATN 4 ABMR 3 ACR 1 There were 8 cases of mortality, 4 in the immediate postop period and 3 during the subsequent 3 months Causes of mortality included Pneumonia, sepsis and liver dysfunction 2 patients developed Covid +Ve Overall the Patient survival was 92 % at 1 year and graft survival 90% Conclusions: kidney transplantation is a viable and practical option for End stage kidney disease and can be performed in resource constrained centers in third world countries Transplants can be performed even during the COVID season with appropriate screening for COVID and probably prophylaxis with Favipiravir No conflict of interest