Atrial myxoma presenting as transient ischaemic attack and acute coronary syndrome in an octogenarian

2006 
An 82-year-old woman was admitted with sudden onset of right arm weakness lasting 4 h. Subsequently, she developed central chest pain. Main physical finding was mid-systolic murmur audible at the apex. Electrocardiograms (ECGs) demonstrated progressive T-wave inversion in the anterior chest leads and atrial fibrillation. Troponin I level was 7.1 ng/dl 12 h post chest pain. Transthoracic echocardiography demonstrated a large mobile mass in the left atrium (Figure 1, available as supplementary data in http://www.ageing.oxfordjournals.org). Cardiac catheterisation was normal. Brain CT suggested acute cerebral infarction in the left frontal lobe. At emergency surgery, a mass (90 55 10 mm) weighing 31 grams was removed from the atrial wall. Myxomas account for the majority of primary cardiac tumours, the left atrium being the commonest site. The peak incidence is between the third and sixth decades [1]. Embolisation, obstruction and arrhythmias are the main modes of presentation [2, 3]. Surgical removal is usually curative [1]. Atrial myxoma is an uncommon but important diagnosis to consider in older people presenting with multiple embolic events.
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