428 ANALYSIS OF ANTI-INFLAMMATORY EFFECTS OF LANSOPRAZOLE ON MACROPHAGES

Conclusions: Our working group has focused on the development of immune markers which useful in the assessment of OA. Pathogenic NA belongs mainly to the IgG isotype. IgG to inflammatory pain agents would be potent diagnostic markers for OA and may play pathogenic roles in the development of OA. Taken together (BK-IgG, DA-IgG, HA-IgG, PGE2-IgG), our results cold promote the understanding of the role of immunity in OA.