Role of thioredoxin reductase 1 and thioredoxin interacting protein in prognosis of breast cancer

Cristina Cadenas,Dennis Franckenstein,Marcus Schmidt,Mathias Gehrmann,Matthias Hermes,Bettina Geppert,Wiebke Schormann,Lindsey J. Maccoux,Markus Schug,Anika Schumann,Christian Wilhelm,Evgenia Freis,Katja Ickstadt,Jörg Rahnenführer,Jörg Ingo Baumbach,Albert Sickmann,Jan G. Hengstler

Role of thioredoxin reductase 1 and thioredoxin interacting protein in prognosis of breast cancer

2010

Cristina Cadenas
Dennis Franckenstein
Marcus Schmidt
Mathias Gehrmann
Matthias Hermes
Bettina Geppert
Wiebke Schormann
Lindsey J. Maccoux
Markus Schug
Anika Schumann
Christian Wilhelm
Evgenia Freis
Katja Ickstadt
Jörg Rahnenführer
Jörg Ingo Baumbach
Albert Sickmann
Jan G. Hengstler

Introduction The purpose of this work was to study the prognostic influence in breast cancer of thioredoxin reductase 1 (TXNRD1) and thioredoxin interacting protein (TXNIP), key players in oxidative stress control that are currently evaluated as possible therapeutic targets.

Keywords:

Cancer research
Thioredoxin-Interacting Protein
Breast cancer
Pathology
Thioredoxin
Thioredoxin reductase
Surgical oncology
Oxidative stress
TXNIP
Medicine
Thioredoxin Reductase 1
Survival rate
Senescence
Downregulation and upregulation

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