Failure to identify an association between serologic or molecular evidence of Bartonella infection and idiopathic rhinitis in dogs

Objective—To determine whether infection with or exposure to Bartonella spp was associated with idiopathic rhinitis in dogs. Design—Case-control study. Animals—44 dogs with idiopathic nasal discharge and 63 age- and weight-matched control dogs without nasal discharge and no clinical signs of bartonellosis. Procedures—Serum was tested for antibodies against Bartonella henselae and Bartonella vinsonii subsp berkhoffii with indirect fluorescent antibody assays. Blood was tested for Bartonella DNA with a PCR assay. Results—Results of the antibody and PCR assays were negative for all 44 dogs with idiopathic nasal discharge. One control dog had antibodies against B henselae; a second control dog had positive PCR assay results. We did not detect a significant association between assay results and group designation. Conclusions and Clinical Relevance—The present study failed to confirm an association between idiopathic rhinitis and exposure to or infection with Bartonella spp in dogs. Findings do not rule out the...