A model system to characterize the personalized immunotherapy, AGS-003, and predict functional activity in combination with other therapeutic agents.

Olga A. Zubkova,Larissa S. Agapova,Marina V. Kapralova,Liudmila A. Krasovskaia,Armen A. Ovsepyan,Maxim V. Lykov,Artem V. Eremeev,Vladimir E. Bokovanov,Olga V. Grigoryeva,Andrey P. Karpov,Sergey V. Ruchko,Charles Nicolette,Alexander M. Shuster

A model system to characterize the personalized immunotherapy, AGS-003, and predict functional activity in combination with other therapeutic agents.

2016

Olga A. Zubkova
Larissa S. Agapova
Marina V. Kapralova
Liudmila A. Krasovskaia
Armen A. Ovsepyan
Maxim V. Lykov
Artem V. Eremeev
Vladimir E. Bokovanov
Olga V. Grigoryeva
Andrey P. Karpov
Sergey V. Ruchko
Charles Nicolette
Alexander M. Shuster

e14532Background: AGS-003 is an immunotherapy consisting of autologous dendritic cells electroporated with amplified total tumor RNA plus synthetic CD40L RNA and is currently being tested in combin...

Keywords:

Immunotherapy
Pathology
Medicine
Pharmacology
functional activity
Autologous dendritic cells
RNA
CD40
model system
Cancer research

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