"Evaluation of efficacy of intradermal injection therapy Vs derma roller application for administration of QR678 Neo® hair regrowth formulation in the treatment of androgenetic alopecia- A Prospective Study".

BACKGROUND Non-surgical hair restoration is one of the most exciting and innovative fields in cosmetic surgery today. The addition of latest technique like dermaroller seeks to achieve better results for delivering pharmaceutical solution for hair growth in compare to topical. AIM We aim to compare intradermal injection vs. dermaroller technique for administration of QR678Neo® hair regrowth therapy for the treatment of Androgenetic Alopecia (AA) in male and female patients. METHOD A sum of 50 patients in the age range of 20-70 years with AA were included& divided into 2 groups; Group A (intradermal) and Group B (derma roller). Intradermal injection of QR678Neo® formulation and dermaroller with superficial application of QR678Neo® was given in each group. Assessment was done using hair pull test, global photographic assessment, video-microscopic assessmentand patient subjective assessment at baseline, 6 months and, 1 year. RESULTS Significant diminution in hair fall was seen in both the groups. All the video microscopic assessment factors were better in intradermalinjection groupcompared to the derma roller group, but not significant. Erythema and pain were high in derma roller group in compare to intradermal. CONCLUSION Derma roller technique is more convenient and easy to perform, especially when the availability of a trained person to carry out intradermal injection is not feasible, it gives satisfactory results. It is also beneficial in needle phobic and apprehensive patients. Though the results are more efficacious with intradermal scalp injection technique, this study established satisfactory results with derma roller technique as well.