In Silico Updates on Lead Identification for Obesity and Cancer

2021 
The prevalence of obesity has risen considerably in previous decades in the modern world, and an additional rise is anticipated in the future decades. Several studies have established that this rise in obesity is accompanied by the elevated risk of cancer occurrence. A number of signaling proteins have been recognized to be related to both obesity and cancer. Computer-aided drug discovery methods have proved their worth in recent times by aiding in the discovery of various lifesaving drugs. Application of in silico methods of drug discovery in the context of obesity and cancer holds significant promise in discovering drugs for the prevention of this problem. In the present chapter, we have provided an overview of common targets in obesity and cancer along with the in silico drug discovery methods that might play a significant role in the discovery of drugs for obesity and cancer.
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