Prevalence and Determinant of Depression among Multi-Drug Resistance Tuberculosis: Study in Dr. Kariadi General Hospital

Backgroud: Multi-drug resistance tuberculosis (MDR-TB) adds the burden of tuberculosis (TB). Depression is a common comorbid in TB patients. Prevalence of depression among MDR-TB patients is higher, i.e. 11-70 %. Prevalence of depression among TB patients in Dr. Kariadi General Hospital was 51.9%. Previous study reported the determinants related to the depression in MDR-TB patients. Current study explores the prevalence of depression in MDR-TB patients and its determinants. Methods: Present study was a cross-sectional study conducted from July-August 2019. Data were obtained from primary and secondary data of Dr. Kariadi General Hospital patients. Sample in this study involved 72 respondents, over 16 years old from 151 registered MDR-TB patients. Depression status was determined by Depression Anxiety Stress Scales obtained from the medical record. Subject’s characteristics and determinants collected from primary as well as secondary data. Descriptive data presented in proportion. Chi-Square test continued by Binary logistic regression was performed to determine the association between depression status and its determinants. P-value < 0,05 considered as statistically significant. Results: Of 72 MDR-TB patients, 26.4% with depression status. Underweight [AOR = 8.24, 95% CI (1.731-39.197)], female patients [AOR = 7.61, 95% CI (1.797-32.213)], presence of comorbidities [AOR = 7.62, 95% CI (1,748-33,204)] and patient’s perseption of stigma in the community [AOR 5.08, 95% CI (1,238-20,826)] are significantly related to the incidence of depression in MDR-TB patients. Conclusion: Prevalence of depression among MDR-TB patients was 26.4%. Underweight, female patient, comorbidity and the patient's perception of stigma were related to depression status.