Autonomic regulation of cardiovascular function in obese rat versus obese human

Among the various health problems associated with obesity, cardiac autonomic neuropathy is one of the serious and relatively under-investigated problems. The authors have previously showed, in 2008, that vagal dysfunction is the main underlying factor in cardiac autonomic neuropathy in a rat model of congenital obesity. The aim of this article is to review the published findings in this topic since  then and to compare the data in rats with those in human subjects. Keywords: Autonomic regulation, obesity, obese rats, obese humans cardiovascular