Right- versus Left-Sided Chest Ports in Oncologic Patients with a History of Right-Sided Port Removal: Are There Any Differences in the Complication Rates?

Abstract Purpose To compare chest port (port)-related complication rates between right- and left-sided ports placed in adult oncologic patients with a history of right-sided port removal. Materials and Methods A retrospective chart review identified 90 adult oncologic patients with a history of right-sided port removal. Of these, 60 patients had a second port placed on the right side (right-side group), while 30 patients had a second port placed on the left side (left-side group). Median time between first port removal and second port placement was 217 days (range, 0–3808 days). Port-related complications included infection (port-site and/or bloodstream), mechanical, thrombotic, and port-site skin complications. Complication rates between groups were compared. Proportional subdistribution hazard regression (PSHREG) was conducted to determine if laterality of the second port is an independent risk factor for port-related complications. Results The cumulative follow-up period was 34,748 catheter-days (median, 233; range, 9–2162 days). Eleven patients (18.3%) in the right-side group and 2 patients (6.7%) in the left-side group had port-related complications ( P = .21), accounting for complication rates of 0.5 and 0.2/1000 catheter-days ( P  = .24), respectively. No statistical difference was found in the incidence of infection (9/60 vs 1/30, P  = .16), mechanical (0/60 vs. 1/30, P  = .33), thrombotic (1/60 vs 0/30, P  = 1.0), and skin-related (1/60 vs 0/30, P  = 1.0) complications between groups. In multivariate PSHREG, laterality of the second port (hazard ratio = 3.09, 95% confidence interval = 0.81–11.76, P  = .10) was not a significant risk factor for port-related complications. Conclusions In adult oncologic patients with a history of right-sided port removal, no significant differences in port-related complication rates were observed between right- and left-sided second ports.