The effectiveness of Du moxibustion for chronic obstructive pulmonary disease A protocol for systematic review and meta-analysis of randomized clinical trials

BACKGROUND As a common respiratory disease, Chronic Obstructive Pulmonary Disease (COPD) develops progressively. Du moxibustion can effectively treat COPD, and no adverse reactions have been reported. This research mainly evaluated the efficacy and safety of Du moxibustion in the treatment of COPD. METHODS Seven databases (PubMed, Cochrane Library, Embase, China National Knowledge Infrastructure (CNKI), Chinese Biomedical Literatures Database (CBM), Wanfang Database (WF), Chinese Scientific Journal Database (VIP)) will be searched for all relevant eligible randomized controlled trials (RCTs) from the date of establishment to January 6, 2021. No matter whether they were blind or not, and regardless of the language and type of publication, these experiments could be included. Two authors (YRZ, ARG) will search the database respectively, extract relevant data, and use the Cochrane bias risk tool to evaluate the quality of the literature. RevMan V5.3 software will be used for data processing. RESULTS The results of this research are mainly used to evaluate the efficacy and safety of Du moxibustion in the treatment of COPD. CONCLUSIONS This systematical review is expected to provide evidence-based and valuable suggestions for Du moxibustion in the treatment of COPD. STUDY REGISTRATION NUMBER INPLASY202110045.