Impaired CD4+ T-Cell Restoration in the Small Versus Large Intestine of HIV-1–Positive South Africans Receiving Combination Antiretroviral Therapy

Gastrointestinal Research Laboratory, Ampath Pathology Laboratories, Pretoria, Department of Anatomical Pathology, and Department of Family Medicine, University of Pretoria, Pretoria, Tshwane Academic Division, National Health Laboratory Service, Johannesburg, and Biomedical Informatics Research, eHealth Research and Innovation Platform, Medical Research Council, Tygerberg, South Africa; and AIDS Immunopathogenesis Unit, Division