Intralesional Pingyangmycin Treatment for Resistant Plantar Warts

Background: The diagnosis of viral warts is often straightforward, but their treatment is difficult and always takes a long time. Nowadays warts are usually treated with conventional methods including topical keratolytic agents, cryotherapy, electrosurgery and laser surgery. However, such treatments cause different complications, and the warts become recalcitrant. Objective: To investigate the effect of intralesional pingyangmycin injection for resistant plantar warts. Methods: From June 2006 to September 2008, we treated 66 patients with plantar warts by intralesional pingyangmycin injection after informed consent. Results: The lesions of 58 patients cleared (87.88%) after up to 4 treatments. The remaining 8 patients (12.12%) achieved partial clearance. No serious side effects were observed. Conclusion: Intralesional injection of pingyangmycin might be an effective, safe and generally well-tolerated treatment for plantar warts.