Cells from Urine Sample

Cells found in the sediment of voided urine of newborns, children and adults can be cultured in vitro. The samples contain many exfoliative cells with different viabilities. The cells originate from the epithelial layer of the kidney pelvis, ureter, bladder, urethra, vagina, and prostate (urothel). The proliferating cells have an epithelial-like appearance. As demonstrated by specific antigens, most of the cells cultured from normal urine are bladder derived (Koskull et al. 1984).