HIV and predictors of advanced cancer at presentation: Uganda.

2014 
6620 Background: The HIV epidemic has contributed to the increasing incidence of cancer in sub-Saharan Africa (SSA), where most patients with cancer present at an advanced stage. However, improved access to HIV care and treatment centers in SSA may facilitate earlier diagnosis of cancer among HIV+ patients. To test this hypothesis, we characterized the stage of cancer and evaluated predictors of advanced stage at presentation among patients in Uganda. Methods: We conducted a retrospective analysis of adult patients who presented for care at 1 of 2 tertiary care sites in Kampala, Uganda with any of 5 specific cancers between 2003 and 2010. Demographic, clinical and laboratory data were abstracted from the medical record along with the outcome measure of advanced stage of disease (clinical stage 3 or 4). We utilized bivariate analyses to identify measures with p<0.20 for inclusion in a multivariate logistic regression model. Results: We analyzed 802 patients with the following cancers: cervical (39%), breas...
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