Mastocitosis cutánea: lo que el pediatra debe saber

Cutaneous mastocytosis (MC) is a heterogeneous group of clinical syndromes characterized by abnormal infi ltration of mast cells in different tissues and concomitant release of chemical mediators by these cells. The etiology is unknown; however, mutations have been described in the c-kit proto oncogene and increased colony stimulating factor. Childhood mastocytosis is classifi ed in urticarial pigmentosa (the most common form), solitary mastocytoma, diffuse cutaneous mastocytosis and telangiectasia macularis eruptive perstans. The diagnosis is clinical, where the appearance of the lesions is used to identify the [ ]