Giant scrotal lipoma: Case report and review of literature

Introduction: Lipoma is a benign mesenchymal neoplasm, the primary scrotal type is extremely rare and most of them develop from the content rather than the wall of the scrotum and they are often confused with liposarcomas clinically. In the few reported cases the largest primary scrotal lipoma to date measured 13.5x10x5 cm. Cytogenetically, 80% of solitary lipomas exhibit chromosomal aberrations, such as rearrangements of 12q13–15, 6p21–22, or deletions of 13q12–14 and 13q22 with 1% tendency of malignant transformation. Case Report: A 42-year-old nomadic Fulani who presented with extremely rare giant primary scrotal lipoma that measured 60x40x12 cm and weighed 38.4 kg. To our knowledge this is the largest scrotal lipoma reported in the literature. Conclusion: Scrotal lipoma can be colossal and leads to diagnostic challenges, especially in developing countries. Total surgical removal of the involved scrotal mass or a compartmental resection has been suggested as treatment of choice; however, the infiltrating type has high chances of local recurrence despite surgical excision. Nevertheless, the tumor rarely transforms into malignancy.