P251 The induction of early, dynamic airway mucosal and systemic immune responses following recent SARS-CoV-2 household exposure

P251 Figure 1Symptom score, virology, serology and nasal & serum cytokine data in the index case and their two PCR-positive household contacts since day of symptom onset at 4 timepoints across 28 days of follow up A Symptom score was calculated by allocating values for each self-reported symptom, weighted by self-reported severity, from a daily tracker;B virology was measured by oropharyngeal swab RT-PCR Samples below the detectable level were assigned value of 1;C-F concentrations of 2 of the cytokines (IFNA1 and IP-10) measured in nasal lining fluid (C & E) and serum (D & F), measured by Meso Scale Discoveries U-plex assay Grey dashed line indicates mean of healthy control values (CEDF52(6):910–41