Organic brain syndrome and long-term exposure to toluene: a clinical, psychiatric study of vocationally active printing workers

This study addresses the prevalence of organic brain syndrome (OBS) among long-term toluene-exposed rotogravure workers who are still working. The prevalence of OBS in 22 workers exposed to toluene for a minimum of 12 years and 19 unexposed control subjects, matched for age and employment status, was assessed with a comprehensive clinical psychiatric interview. There was a significantly greater prevalence of mild chronic encephalopathy and organic affective syndrome in the toluene-exposed group.