Prognostic significance of dynamics of biochemical markers of neuroendocrine tumors during treatment with biotherapy

Dynamic of biochemical markers of neuroendocrine tumors (chromogranin A, serotonin, 5-hydroxyindoleacetic acid) are predictive factorsof biotherapy efficacy. We found that 30% decreasing of biochemical markers within 6 months improves median of time to progression for patients with neuroendocrine tumors.