Inhibitory activity of ginkgolic acids from ginkgo sarcotesta against pathogenic fungi and bacteria.

The hypha growth rate method and culture medium coating method were used to determine the inhibitory activity of ginkgolic acids from ginkgo sarcotesta against 9 plant pathogenic fungi and 10 animal pathogenic bacteria.The results showed that ginkgolic acids had inhibitory activity against such 9 plant pathogenic fungi as Cercospora kaki,Pyricularia oryzae,Gymnosporangium haraeanum,Colletotrichum graminicola,Sphaceloma fawcettii,Thielaviopsis paradoxa,Fusarium oxysporum f.sp.niveum,Mycosphaerella sentina and Glorosprium mussruum.The EC50 values were 0.6657-19.5580g/L.The inhibitory activity against Glorosprium mussruum was the highest and that against Pyricularia oryzae,the lowest.Ginkgolic acids also had inhibitory activity against 10 animal pathogenic bacteria,and the inhibitory activity against Bacillus megaterium and Bacillus subtilis was the highest,with the MIC values of 1.25g/L.