Blood coagulation parameters in patients with lichen planus
2004
: The aim of this study was to evaluate some blood parameters of coagulation process in blood plasma of patients suffering from lichen planus. The study group consisted of 23 patients--14 women and 9 men, aged 33-75 years. Control group contained 30-age matched healthy persons. In blood of plasma the following parameters were determined: activity of antithrombin III (AT III) and concentration of prothrombin fragments 1+2 (F1+2), complexes thrombin-antithrombin III (TAT). In blood plasma of patients with lichen planus the concentration of F1+2 was significantly higher than in healthy persons. Increased concentration of F1+2 indicated intensive thrombinogenesis in vivo in patients with lichen planus.
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