Four routinely recorded parameters define four distinct prognostic groups in AML.

6584 Background: Prediction of outcome in AML is crucial for patient counselling and therapy allocation. While numerous factors have been studied, they should be easily accessible for routine application. The best established prognostic factors are karyotype and age. However, performance status as measured by the ECOG may play an important role in the outcome of AML. Methods: 198 consecutive patients with AML were retrospectively analysed, irrespective of the applied therapy. Median age was 62 years (range 20-81) with approximately even sex distribution (95 male). Karyotype was 11.6 % good (score 0), 68.0 intermediate (score 1) and 20.4 % poor risk (score 3), respectively. The median survival was 382 days. The criteria of the Eastern Collaborative Oncology Group performance score (ECOG) were applied. Age older than 60 years and secondary leukemia were scored with 1 point, respectively. Patients were classified into four prognostic groups according to cumulative score, namely very good (0), good (1), poor ...