Comparison of virtual tissue quantification and strain ratio of ultrasonic elastographpy in differential diagnosis of benign or malignant breast lesions

2012 
Objective To compare the diagnostic value of virtual touch tissue quantification(VTQ) and strain ratio(SR) method in differentiating benign or malignant breast lesions.Methods Totally 103 patients with 126 breast lesions were examined with UE to get SR,then with VTQ technique to get VTQ of the lesions,respectively.Taking pathological results as golden standard,ROC curves were constructed to evaluate the diagnostic value of these methods.Results The best cutoff point of VTQ for diagnosis of malignant lesions was 6.64 m/s,and the area under ROC curve was 0.88.The sensitivity,specificity and accuracy rate of the VTQ was 82.61%(19/23),100%(103/103) and 96.83%(122/126),respectively.And the area of ROC curve for SR method was 0.87.There was no statistical difference between these two diagnostic methods in the area under ROC curve(P0.05).Conclusion VTQ is helpful to evaluation of benign or malignant of breast lesions.And it has the same diagnostic value as SR method.
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