A Case Report on Disseminated Non-Epidemic Kaposi Sarcoma in Non-HIV Non-Organ Transplant Heterosexual Yemeni Man: A Discussion of Possible Etiology

Kaposi’s sarcoma (KS) is the most prevalent malignancy in patients with HIV infection. few reports describe KS in HIV-negative, non-immune compromised patients in the United States, but the incidence of the disease in the area of middle east in non-HIV, Immunocompetent is not well recognized. It affects the endothelial cells of the skin and mucous membranes. The cases seen in HIV-negative men were less aggressive and rapidly progressing than those in people with HIV. However, although, they tended to be more malicious than in the classical type of KS which is seen mostly in men of Mediterranean origin and occurred at an earlier age. We are presenting a rare case of Mucocutaneous KS diagnosed based on histopathology in an 82-year-old Yemeni male patient, who is seronegative HIV, non-immunocompromised with no history of organ nor bone marrow transplantation.