Role of caudomedial portion in left and right cingulum bundle in perceptual and emotional components of nociception in rats

The effects of electrocoagulation of caudomedial portion of the left and right cingulum bundles on tail-flick latency and vocalization threshold were examined on rats. We revealed a tendency to a decrease in the tail-flick latency and more pronounced elevation of the vocalization threshold after destruction of the right cingulum bundle. These findings indicate functional asymmetry of the cingulum bundle in the realization of the emotional nociceptive reaction.