Linfohistiocitosis hemofagocítica y otros trastornos asociados. Pertinencia del uso de gamaglobulina

Autoimmune diseases are characterized by a immunological dysregulation; they present a misinterpretation by the patient’s immune system against it’s own antigen where takes place any hypersensibility response of Gel-Coombs mechanisms. There exist many kind of hemophagocytic syndromes, besides of it’s origin worldwide this entity has a high mortality and there’s no standardized therapeutic alternative. Diverse elements like etoposide, glucocorticoids, cyclosporine and also gammaglobulin to mention some have been used for trying to stop hemophagocytosis. In practice, Still disease has been increased in incidence, it can develop hemophagocytic syndrome, that’s why is important the clinical manifestations, workup and treatment.