Diffusion-weighted Imaging of the Liver with Multiple b Values: Effect of Diffusion Gradient Polarity and Breathing Acquisition on Image Quality and Intravoxel Incoherent Motion Parameters—A Pilot Study

Intravoxel incoherent motion can be applied for liver fibrosis detection with good image quality and acceptable reproducibility by using a respiratory-triggered bipolar diffusion-weighted sequence and has potential to enable users to distinguish between healthy subjects and patients with a fibrotic liver.