Parvovirus B19 Infection as a Rare Cause of Fulminant Liver Failure

Abstract Parvovirus B19 infection is common in childhood. The clinical presentations ranges from benign to life threatening. Literature points that clinical presentation is influenced by the patient’s age and presence of any chronic disease such as chronic hemolytic disorders and immunosuppressed conditions. As the majority of patients with liver failure are diagnosed as indeterminate, knowledge about Parvovirus B19 associated liver disease is limited. We present three children with Parvovirus B19 induced fulminant liver failure of whom two underwent liver transplantation. Although presented patients received standart corticosteroid and tacrolimus therapy as immunosupressive regimen, acute rejection, Parvovirus B19 persistence or any other complication due to Parvovirus B19 did not observed. Physicians should be aware of the Parvovirus B19 infection in association of acute liver diseases.