Effect of N(Epsilon)-(carboxymethyl)lysine on Laboratory Parameters and Its Association with βS Haplotype in Children with Sickle Cell Anemia

Uche Samuel Ndidi,Corynne Stephanie Ahouefa Adanho,Rayra Pereira Santiago,Sètondji Cocou Modeste Alexandre Yahouédéhou,Sanzio Silva Santana,Vitor Valério Mafili,Thassila Nogueira Pitanga,Cleverson Alves Fonseca,J Ferreira,Elisângela Vitória Adorno,Isa Menezes Lyra,Adekunle D. Adekile,Cynara Gomes Barbosa,Marilda de Souza Gonçalves

Effect of N(Epsilon)-(carboxymethyl)lysine on Laboratory Parameters and Its Association with βS Haplotype in Children with Sickle Cell Anemia

2019

Uche Samuel Ndidi
Corynne Stephanie Ahouefa Adanho
Rayra Pereira Santiago
Sètondji Cocou Modeste Alexandre Yahouédéhou
Sanzio Silva Santana
Vitor Valério Mafili
Thassila Nogueira Pitanga
Cleverson Alves Fonseca
J Ferreira
Elisângela Vitória Adorno
Isa Menezes Lyra
Adekunle D. Adekile
Cynara Gomes Barbosa
Marilda de Souza Gonçalves

The present study aimed to investigate the association of Ne-carboxymethyllysine (CML) with laboratory parameters and βS haplotypes in pediatric sickle cell anemia (SCA) patients with or without hydroxyurea (HU) therapy. We included 55 children with SCA (SCAtotal), where 27 were on HU treatment (SCA-HU

Keywords:

Genetics
Haplotype
Diabetes mellitus
Sickle cell anemia
Lysine
Immunology
Biology
Creatinine
Lactate dehydrogenase
Atypical Lymphocyte
Internal medicine
Endocrinology
Aspartate transaminase
Alanine transaminase

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