Abstract 14553: Mitochondrial Calcium Uptake via Mitochondrial Calcium Uniporter Suppress Ventricular Arrhythmia in the Ischemic Heart Failure Mice

Hikaru Hagiwara,Masaya Watanabe,Yoichiro Fujioka,Taro Koya,Motoki Nakao,Yumi Takahashi,Rui Kamada,Yusuke Ohba,Toshihisa Anzai

Abstract 14553: Mitochondrial Calcium Uptake via Mitochondrial Calcium Uniporter Suppress Ventricular Arrhythmia in the Ischemic Heart Failure Mice

2020

Hikaru Hagiwara
Masaya Watanabe
Yoichiro Fujioka
Taro Koya
Motoki Nakao
Yumi Takahashi
Rui Kamada
Yusuke Ohba
Toshihisa Anzai

Background: Delayed after depolarization by calcium (Ca2+) leak from sarcoplasmic reticulum (SR) via Ryanodine receptor is one of the causes of ventricular arrhythmias (VAs) in heart failure (HF). ...

Keywords:

Pharmacology
Medicine
ischemic heart
Mitochondrial calcium uniporter
Mitochondrial calcium uptake

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