Mortalidad asociada a factores de riesgo para cáncer de mama en mujeres

Breast cancer is the leading cause of malignancy in women and is a major cause of mortality, annually it is responsible for 458 000 deaths worldwide (Cancer, 2013). There are many risk factors, both modifiable and non-modifiable, associated with the disease and the mortality of it. In the current study, conducted in the Oncology area of the Hospital Carlos Andrade Marin in Quito, Ecuador, in the period August 2011 to August 2013, were investigated nine variables including: age at diagnosis, age at menarche, number of children, family history, consumption of alcohol and tobacco, levels of hemoglobin and platelets at the time of diagnosis prior medical treatment and triple negative phenotype. 463 women were evaluated, the mean age was 56 years and approximately 16% of patients had triple negative phenotype. The only two statistically significant values found were age and triple negative phenotype. The OR for age was 6,75 (95% CI 0,905 – 50,299; p value 0,000), which means that if a women has more than 40 years has 6,75 times more chances to die. In the case of triple negative phenotype, the OR is 2,38 (95% CI 1,228 – 4,584; p value 0,010), which indicates that there is 2,38 more risk to die in comparison with the other patients. In conclusion, these two variables directly influence the mortality rates of patients diagnosed with the disease.