Using a machine learning approach to identify low-frequency and rare filaggrin alleles associated with remission of atopic dermatitis
2021
Abstract: Atopic dermatitis (AD) is a common relapsing inflammatory skin disease. Filaggrin (FLG) is the gene most consistently associated with AD. Loss-of-function (LoF) variants in FLG have been previously associated with AD. Low-frequency and rare alleles (minor allele frequency
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