Aggressive Lymphoma in Children and Adolescents

Non-Hodgkin lymphomas (NHL) account for 7% of childhood malignancies between the ages of 0 and 19 according to SEERS data from 2010 to 2014. NHL are rare in early childhood with an incidence of 7.3/106 children/year in the 1–4-year age group. By adolescence, the annual incidence rises with 14/106 children in the 10–14-year age range and 18.3/106 children in the 15–19-year age group. In addition, lymphoblastic leukemia accounts for another 20% of childhood cancers making malignancies of lymphatic origin the largest group of childhood cancers.