Overview of Microsatellite Instability and Immune Checkpoint Inhibitors in Colorectal Cancer

Dae Won Kim,Jung-hoon Lee,Kunhwa Kim,Iman Imanirad

Overview of Microsatellite Instability and Immune Checkpoint Inhibitors in Colorectal Cancer

2018

Dae Won Kim
Jung-hoon Lee
Kunhwa Kim
Iman Imanirad

Purpose of Review This review examines the pathophysiological features of microsatellite instability (MSI) high colorectal cancer and discusses recent clinical studies of immune checkpoint inhibitors for MSI high colorectal cancer.

Keywords:

Microsatellite
Pathology
Colorectal cancer
Cancer research
Immune checkpoint
Microsatellite instability
Medicine
immune checkpoint inhibitors
cancer therapy
Blockade
Tumor microenvironment
immunogenic tumor
Colorectal surgery

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