Recent advances in the synthesis of fused heterocycles with new skeletons via alkyne cyclization

Abstract An account of our most recent developments on the synthesis of various fused heterocycles via alkyne cyclization is presented. The synthetic strategy involves N- or O-propargylation of heteroaromatic or aromatic compounds followed by intramolecular gold-catalyzed or NaH-promoted intramolecular cyclization reactions. This synthetic strategy represents a reasonable methodology for the construction of hitherto unknown skeletons.