Abstract 805: A Toll-like Receptor 9 Inhibitor Prevents the Development and Progression of Sterile Inflammatory Heart Failure Induced by Mitochondrial DNA Accumulation

Hiromichi Ueda,Manabu Taneike,Kinya Otsu,Yasushi Sakata

Abstract 805: A Toll-like Receptor 9 Inhibitor Prevents the Development and Progression of Sterile Inflammatory Heart Failure Induced by Mitochondrial DNA Accumulation

2019

Hiromichi Ueda
Manabu Taneike
Kinya Otsu
Yasushi Sakata

Mitochondrial DNA contains unmethylated cytidine-phosphate-guanosine motif, and is recognized by Toll-like receptor (TLR) 9, inducing sterile inflammation. We previously reported that the accumulat...

Keywords:

Cardiology
Biology
Internal medicine
Diabetes mellitus
Cancer research
Mitochondrial DNA
Heart failure
Toll-Like Receptor 9

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