Racial/ethnic disparities in clinicopathologic features and treatment modalities of triple-negative breast cancer in black premenopausal women.

58 Background: Triple-negative breast cancer (TNBC) is a distinct breast cancer subtype associated with poor outcomes. Previous literature has reported an increased prevalence of TNBC in premenopausal black women. However, clinicopathologic features and treatment disparities of TNBC require further investigation. Methods: We used the Surveillance Epidemiology and End Results (SEER) database to collect data for premenopausal, estrogen receptor–negative, progesterone receptor–negative, and HER2 receptor–negative invasive breast-cancer cases diagnosed in 2010. Blacks were compared to the referent non-Hispanic white (NHW) cohort. Variables explored include: age at diagnosis, summary stage, tumor size, presence of metastasis at diagnosis, birth country, marital status, radiation, surgery (total and partial mastectomy), and radiation/surgery sequence. The Kruskall-Wallis test and the Z-test were used to investigate for any racial/ethnic disparities that may exist. Results: Compared to NHW, black patients had mo...