Preclinical safety and immunological efficacy of Alternaria alternata polymerized extracts: Efficacy and safety of Alternaria alternata allergoid extract

Introduction Alternaria alternata is a widespread fungi whose allergy is a risk factor for asthma development. The use of a polymerized allergen extract (allergoid) may be safer than native extract based treatments while maintaining efficacy. The objective of this study was to characterize biochemically and immunochemically a new Alternaria alternata allergoid.