To strengthen the prevention and treatment of postoperative complications of thyrotoxicosis in secondary hyperparathyroidism patients with end-stage renal disease

Chronic kidney disease, especially in patients with end-stage renal disease (ESRD) , is prone to causing secondary hyperparathyroidism, and part of refractory secondary hyperparathyroidism patients require treatment with parathyroidectomy. Parathyroidectomy makes the thyroid inevitably subject to mechanical stimulation, leading to transient mechanical thyroiditis, hyperthyroxinemia and postoperative transient thyrotoxicosis, causing dysfunction in multiple systems of the body, and even inducing or aggravating water and electrolyte disorders (such as hyperkalemia) , arrhythmia and cardiovascular events. However, this complication has not yet received sufficient clinical attention. This article will discuss the prevention and treatment of thyrotoxicosis or hyperthyroidism, one of the postoperative complications, in secondary hyperparathyroidism patients with ESRD, based on the relevant documents and our own clinical practice. Key words: Secondary hyperparathyroidism; Parathyroidectomy; Transient mechanical thyroiditis; Transient thyrotoxicosis; Transient hyperthyroxinemia