Continuous Noninvasive Blood Pressure Monitoring of Beat-by-Beat Blood Pressure and Heart Rate Using Caretaker® Compared to Invasive Arterial Catheter In the Intensive Care Unit

Structured Abstract Objective We aimed to examine the accuracy of noninvasively-derived peripheral arterial BP by Caretaker device (CT) against invasively measured arterial BP. We also examined the fidelity of heart rate variability by CT compared to ECG derived data. Design Prospective cohort study. Participants Adult surgical and trauma patients admitted to the ICU. Setting Academic tertiary care medical center. Interventions In a prospective manner, beat-by-beat BP by CT was recorded simultaneously with invasive arterial BP measured in patients in the intensive care unit. Invasive arterial BPs were compared with those obtained by the CT system. All comparisons between the CT data, arterial catheter data, and ECG data were post-processed. Measurements and Main Results From 37 enrolled patients, 34 were included with satisfactory data that overlapped between arterial catheter and CT. A total of 87,757 comparative data points were obtained for the 40 minute time window comparisons of the 34 patients, spanning approximately 22.5 hours in total. Systolic BP and diastolic BP correlations (Pearson's coefficient), as well as the mean difference (standard deviation) were, 0.92 and -0.36 (7.57) mmHg and 0.83 and -2.11 (6.00) mmHg, respectively. The overall inter-beat correlation was 0.99 with the mean difference between inter-beats obtained with the arterial BP and the CT was -0.056ms (6.0). Conclusions This study validates the non-invasive tracking of BP using the CT device and the pulse decomposition analysis approach is possible within the guidelines of the standard.