New triterpenoid saponins from Patrinia scabiosaefolia.

Abstract Phytochemical investigation of the methanol extract from the whole plants of Patrinia scabiosaefolia Fisch. resulted in the isolation of four new triterpenoid saponins ( 1 – 4 ) along with six known compounds ( 5 – 10 ). On the basis of spectroscopic and chemical methods, the structures of the new compounds were established as 3- O -β- d -xylopyranosyl-(1→3)-α- l -rhamnopyranosyl-(1→2)-β- d -xylopyranosyl-12β,30-dihydroxy-olean-28,13β-olide ( 1 ), 3- O -α- l -rhamnopyranosyl-(1→2)-β- d -xylopyranosyl-12β,30-dihydroxy-olean-28,13β-olide ( 2 ), 3- O -β- d -xylopyranosyl-(1→2)-β- d -glucopyranosyl-12β, 30-dihydroxy-olean-28,13β-olide ( 3 ), and 3- O -β- d -glucopyranosyl-(1→4)-β- d -xylopyranosyl-(1→3)-α- l -rhamnopyranosyl-(1→2)-β- d -xylopyranosyl-oleanolic acid 28- O -β- d -glucopyranoside ( 4 ), respectively. Compounds 1–3 possess a novel 12β,30-dihydroxy-olean-28,13β-lactone aglycone and a 12β-hydroxy substituent that is rarely found in this kind of triterpenoid saponin.