Orbital involvement in multiple myeloma

Purpose To present the case report of a patient with multiple myeloma who develops orbital infiltration in the left side due to the myeloma. Methods A 53-year-old male with the diagnosis of IgA-kappa multiple myeloma 3 years ago, stage III B in the staging system of Durie and Salmon, who has increased the volume in the left upper eyelid region in recent months. On examination the patient had moderate ptosis without affecting the pupillary axis, exophthalmos of 22.5 mm, hypotropia in primary position of gaze and limitation of supraversion left eye. Radiological and histological findings confirmed the existence of orbital extension of multiple myeloma at the supero-internal quadrant. Results The patient has received several lines of chemotherapy treatment and autologous bone marrow transplantation without systemic or orbital improvement. Because of its systemic poor condition has been rejected surgical treatment and radiotherapy to the orbital level. Conclusion Although orbital involvement is rare and there are few reports in the literature, a patient with multiple myeloma who presents proptosis and / or increased the orbital volume, we must consider orbital infiltration by myeloma however, definitive diagnosis is histological.